Estimation of antimicrobial resistance of Mycoplasma genitalium, Belgium, 2022

The study reveals that over half of MG-positive samples in Belgium harbor resistance-associated mutations (RAMs) to macrolides, the primary treatment for MG. This is particularly prevalent in men who have sex with men (MSM), with 45% being resistant. The presence of fluoroquinolone RAMs was around 26%. The findings suggest that testing for macrolide resistance among MSM might not be necessary in Belgium, but are crucial in other populations due to lower prevalence and emerging fluoroquinolone resistance.